Population risk stratification for early detection and unintended consequences
Programme stream(s): Early detection / diagnosis and prognosis , Prevention
Programme session type(s): Parallel session
Speaker: Adam Brentnall, Queen Mary University of London
Speaker: Ros Eeles, Institute of Cancer Research
Speaker: Ian Tomlinson, University of Birmingham
Date and time: Sun 03-Nov-2019, 5:05 pm-6:35 pm
The session will provide overviews of the current state of the art using common genetic variants (SNPs) in a polygenic risk score (PRS) and other factors using existing risk algorithms.
The session will concentrate on 3 major cancers providing the commonest male (prostate) and female cancers (breast) and another (colorectal) with fairly equal impact.
As there are widely used screening tests for each and potential for harm particularly in lower risk individuals this will provide a good overview of where risk stratification currently stands.