Programme stream(s): Cancer discovery / underpinning research
Speaker: Colm Ryan, University College Dublin, Ireland
Speaker: Jason Moffatt, University of Toronto, Canada
Speaker: Rachael Natrajan, The Institute of Cancer Research, UK
Date and time: Mon 05-Nov-2018, 2:00 pm-4:00 pm
The molecular re-writing that is associated with the tumorigenic process, as well as driving many of the well-established hallmarks of cancer, also generates a series of vulnerabilities in cells, including gene addiction and synthetic lethal interactions. This session will discuss how these vulnerabilities might be identified, understood and ultimately exploited in the development of new therapeutic approaches for cancer, and will include insights from both computational as well wet lab biology. By the end of this session participants will gain an understanding of methods and approaches to identify and dissect genetic interactions in tumour cells.