Alex Snyder

snyder---alexandraPhysician scientist
Memorial Sloan Kettering Cancer Centre

Dr. Snyder is a translational physician scientist at Memorial Sloan Kettering Cancer Centre (MSKCC ) who specialises in tumour genetics and response to checkpoint blockade immunotherapy in solid tumours.  Dr. Snyder received her bachelor’s degree in History at Princeton University, and her MD at the Mount Sinai School of Medicine.  She completed internal medicine training at Mount Sinai Hospital and medical oncology fellowship at MSKCC, where she was Chief Fellow.  She now practices as part of the Gynecologic Medical Oncology and Immunotherapeutics services at MSKCC.  Her prior studies highlighted the correlation between elevated mutation and neoantigen burden and clinical benefit to checkpoint blockade therapies in metastatic melanoma and lung cancers and demonstrated that a neoantigen-specific T cell response could be measured in the peripheral blood in these patients.  Her current work extends these methodologies to incorporate RNA expression and T cell receptor sequencing data, providing an integrated description of the tumour and tumour microenvironment.  Her work now focuses particularly on genitourinary malignancies.