All our speakers are handpicked based on their expertise in the field; allowing them to share their groundbreaking research or discuss an important area of policy, as well as provide an overview of the topic. We’re excited to share some fantastic speakers with you for our 2020 Virtual Events Programme, but make sure you check back for updates as we continue to confirm more!View virtual events programme
Memorial Sloan Kettering Cancer Center, USARead biography
Dr. Papaemmanuil is an Assistant Attending Computational Oncologist in the Department of Epidemiology and Biostatistics and an Affiliate Member of the Cancer Genetics and Biology Programme. She is affiliated with the Marie-Josée and Henry R. Kravis Center for Molecular Oncology and is the Associate Director for the Center of Hematological Malignancies.
Dr Papaemmanuil was trained in Human Molecular Genetics at the University of Glasgow, completed PhD studies in Population Genetics and Epidemiology, and conducted her postdoctoral research at the Cancer Genome Project at the Wellcome Trust Sanger Institute in Cambridge UK. Dr Papaemmanuil is a certified computer systems and operations development analyst by the British Society of Computing.
Dr Papaemmanuil’s research is focused on developing comprehensive laboratory and novel analytical methodologies to study the role of acquired mutations in cancer, and how these define clinical phenotype and determine therapeutic response. Dr Papaemmanuil works with large and well-annotated clinical trial cohorts to study the diagnostic, prognostic and predictive value of genomic variation and how this knowledge can guide the development of future clinical protocols. To this effect, she is leading a number of international multi-centre consortia including the prospective molecular characterization for the International Working Group in myelo-displastic syndromes, the pan-myeloid meta-analysis, and genome profiling of the UK acute lymphocytic leukaemia clinical trials. At MSK, Dr Papaemmanuil leads integrative whole genome, transcriptome and methylation studies of spatially and temporally separated samples in pediatric tumours. These studies are focused on understanding the genomic and clonal structure of pediatric genomes at diagnosis and how these change during therapy, and importantly, disease progression. Informed by genomic findings, Dr Papaemmanuil uses primary patient tissues to study the biological consequences of disease defining mutations in cancer using single-cell and iPSC cell lies.
Dr Papaemmanuil is a European Society of Hematology Fellow, an American Society for Hematology Scholar, and a Josie Robertson Investigator.
Scripps Research Translational Institute, USARead biography
Eric Topol is the Founder and Director of the Scripps Research Translational Institute, Professor, Molecular Medicine, and Executive Vice-President of Scripps Research.
As a researcher, he has published over 1,200 peer-reviewed articles, with more than 270,000 citations, elected to the National Academy of Medicine, and is one of the top 10 most cited researchers in medicine. His principal scientific focus has been on the genomic and digital tools to individualize medicine.
In 2016, Topol was awarded a $207 million grant from the NIH to lead a significant part of the Precision Medicine (All of Us) Initiative, a prospective research program enrolling 1 million participants in the US. This is in addition to his role as principal investigator for a flagship $35M NIH grant to promote innovation in medicine. He has been voted as the #1 most influential physician leader in the United States in a national poll conducted by Modern Healthcare. Besides editing several textbooks, he has published 3 bestseller books on the future of medicine: The Creative Destruction of Medicine, The Patient Will See You Now, and Deep Medicine: How Artificial Intelligence Can Make Healthcare Human Again. Topol was commissioned by the UK 2018-2019 to lead planning for the National Health Service’s integration of AI and new technologies.
|Karin de Visser
The Netherlands Cancer Institute and Oncode Institute, The NetherlandsRead biography
Prof. Dr Karin E. de Visser obtained her PhD at the Division of Immunology at the Netherlands Cancer Institute in Amsterdam in the field of tumour immunotherapy.
From 2003-2005 she worked as a postdoctoral fellow in the lab of Prof. Dr Lisa Coussens at the University of California, San Francisco, where she developed an active interest in the interplay between the adaptive and innate immune system during cancer development. In 2005 she joined the laboratory of Prof. Dr Jos Jonkers at the Netherlands Cancer Institute, where she expanded her research direction into the field of inflammation and mammary carcinogenesis, using conditional mouse models. Currently, she is a senior group leader at the Division of Tumor Biology & Immunology at the Netherlands Cancer Institute, alongside her appointment as a group leader at Oncode Institute and as professor of Experimental Immunobiology of Cancer at Leiden University Medical Center. The overall goal of her research is to understand which mechanisms the immune system influences metastatic breast cancer. Her research group identified how mammary tumours induce a systemic inflammatory response that facilitates metastasis formation (Coffelt et al. Nature 2015) and how the genetic make-up of breast cancer dictates systemic pro-metastatic inflammation (Wellenstein et al. Nature 2019). Through mechanistic understanding of the crosstalk between the immune system and cancer she aims to contribute to the design of novel immunomodulatory strategies to fight metastatic breast cancer.
Karin de Visser received an ERC consolidator grant in 2014 and a prestigious NWO-VICI grant in 2019, she is the recipient of the 2015 Metastasis Research Prize of the Beug Foundation and in 2016 she was selected as a member of the EMBO young investigator program. More information can be found here: https://www.nki.nl/divisions/tumor-biology-immunology/de-visser-k-group/
University of California San Francisco, USARead biography
Vinay Prasad MD MPH is a practicing hematologist-oncologist and Associate Professor of Medicine at the University of California San Francisco.
He studies cancer drugs, health policy, and evidence-based medicine. He is author of over 240 academic articles, and the books Ending Medical Reversal (2015), and Malignant (2020). He hosts the oncology podcast Plenary Session and tweets @VPrasadMDMPH.
McGill University, CanadaRead biography
William D. Foulkes, M.B.BS, Ph.D., F.R.S.C. is a James McGill Professor in the Departments of Human Genetics and Oncology at McGill University, Montreal, Canada. He is senior clinician-scientist who has worked in the area of inherited susceptibility to cancer for over 25 years.
His research career centres on understanding inherited susceptibility to cancer. The direction of his program has been to move from cancer gene mutation discovery to clinical applications. This work is intimately associated with his clinical career: this process has enabled him to directly use patients as a source of discovery and to rapidly translate the results of our work for the benefit of patients and their families. Over the years, he has supervised many undergraduate and graduate students as well as research and medical fellows. To complement his own expertise, he has developed a broad collaborative network of clinical, pathology and basic research experts with relevant specialities that are systematically involved in all aspects of his research program.