Gene editing: Technology to therapy

Host: Jacqueline Boultwood, University of Oxford

09:00-11:00

Room: Room 11

Recent advances in genome editing, most notably the advent of CRISPR/Cas9 technology, are revolutionising many areas of cancer research. In this session the speakers will provide an overview of genome editing approaches and discuss the application of these tools to cancer research. Topics covered will include the use of CRISPR/Cas9 gene editing in disease modelling and genome-wide functional screens, with a focus on the identification of therapeutic targets. CRISPR-mediated gene regulation will also feature.

Confirmed speakers;
Luigi Naldini, San Raffaele Telethon Institute for Gene Therapy, Italy
George Vassiliou, Wellcome Trust Sanger Institute, UK
Jarno Drost, Princess Máxima Center for Pediatric Oncology, The Netherlands

From CRISPR-Cas9 drop-out screens to novel therapeutic approaches in acute myeloid leukaemia
Modelling cancer in human stem cell organoid cultures